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De-extinction scientists say these gene-edited ‘woolly mice’ are a step toward woolly mammoths

Published On: March 29, 2025Categories: Planetary health, Technology

By Jessica Hamzelou

They’re small, fluffy, and kind of cute, but these mice represent a milestone in de-extinction efforts, according to their creators. The animals have undergone a series of genetic tweaks that give them features similar to those of woolly mammoths—and their creation may bring scientists a step closer to resurrecting the giant animals that roamed the tundra thousands of years ago.

“It’s a big deal,” says Beth Shapiro, chief science officer at Colossal Biosciences, the company behind the work. Scientists at Colossal have been working to “de-extinct” the woolly mammoth since the company was launched four years ago. Now she and her colleagues have shown they can create healthy animals that look the way the team wants them to look, she says.

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