Mast Cell Activation Syndrome
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Mast Cell Activation Syndrome: The Hidden Culprit Behind Mysterious Multi-System Symptoms

Published On: August 19, 2025Categories: Immune Health, Personalized Medicine

Dr. Jill C. Carnahan, MD, ABIHM, IFMCP

Have you ever experienced seemingly unrelated symptoms affecting multiple body systems—unexplained rashes, digestive issues, brain fog, heart palpitations—that doctors can’t quite figure out? You might have been told it’s “all in your head” or given a patchwork of diagnoses that don’t quite explain the full picture of your health struggles. As a functional medicine physician, I’ve seen countless patients with these complex constellations of symptoms who have been misdiagnosed, dismissed, or left without answers for years. Many of them are suffering from Mast Cell Activation Syndrome (MCAS)—a condition that’s gaining recognition but remains poorly understood by many healthcare providers.

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