Gut Microbiome

Gut Microbiome-Trained T Cells Help Heal Injured Muscles and Liver

Published On: March 15, 2023Categories: Microbiome

Studies in mice by Harvard Medical School (HMS) researchers suggest how a class of regulatory T cells (Tregs) that are produced in the gut also play a role in repairing injured muscles and mending damaged livers.

The research found that gut microbiota fuel the production of, and act as the training camp for, a class of immune cells—RORγ+ Tregs—that are recruited to heal muscle injury. The study findings also indicated that these same gut immune cells help repair injured fatty livers. The collective results suggest that these Tregs act as immune healers that go on patrol around the body and respond to distress signals from distant sites of injury.

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