Cardiometabolic Function: The Intersection Among Neurology, Endocrinology, and Immunology

Cardiometabolic conditions may be the most identifiable, tested, and conventionally treated in medicine. Cardiometabolic risk (CMR) refers to risk factors that increase the likelihood of experiencing vascular events or developing diabetes. These conditions also pose the greatest risk of death, which is why they are a focus of conventional care. As functional medicine providers increase in demand, the demand for the functional approach to cardiometabolic conditions will also rise. Training functional providers on the importance of cardiometabolic evaluations, creating comfort in the recommendations for “risky” conditions, and connecting the body systems are essential. Every functional medicine provider sees patients that have been evaluated for cardiometabolic health are currently showing early signs of dysfunction, and have the opportunity to intervene in the 10-year period between dysfunction and disease.

During the 10-year period between dysfunction and disease, clinicians encounter patients showing neurological dysfunction with things such as low heart rate variability, irregularities in heart beats, and even blood pressure. Some of these intertwine with hormones, such as stress hormones like cortisol and sex hormones, as seen in the increase in female heart disease risk after menopause. With inflammation at the heart of any chronic disease, it’s undeniable that the immune system plays a role, as well. One of the largest sources of body inflammation can come from chronic infections or the gastrointestinal tract. Everything is connected, and functional medicine provides the avenue to connect the early data points for a more successful intervention.

Clinical Challenges of Cardiometabolic Diseases:

One of the struggles encountered when treating cardiometabolic disease is the lifestyle change required by the patient. The most successful interventions involve improvement in dietary choices, exercise, and stress reduction. In the consumer market, you see many people taking advantage of the opportunities that wearables offer to monitor their own sleep, glucose, HRV, diet, and even movement levels. Integration of these wearables into actionable plans can create a working relationship between physicians and patients in a way that motivates patients and keeps them accountable.

This Conference:

For PLMI 2023, topics such as insulin resistance, inflammation, cholesterol, and blood pressure will be addressed, but through the lens of new innovative ways of both assessing and managing these conditions from a functional perspective. This conference will focus on new tools and interventions that improve both patient compliance and outcome. We are witnessing a virtual revolution in developing and clinically applying new methods for managing these complex metabolic conditions. These advances frame the focus on this conference as the next chapter in the clinical solutions series of conferences co-hosted by the Personalized Lifestyle Medicine Institute and Orthomolecular Products. This will be a “how to” conference and a “what to do” introduction to the latest in new clinical procedures.

Hourly Schedule

Day One April 21, 2023

7:00am - 8:00am
Registration and Breakfast
8:00am - 8:05am
Welcome and Introduction
8:05am - 9:00am
The Clinical Connection Among Metabolic Fitness, Immunity and Cardiometabolic Diseases
Speakers:
Jeff Bland, PhD
9:00am - 10:00am
What Do Dementia, Depression and Adiposity have in common?
Speakers:
Austin Perlmutter, MD
10:00am - 10:30am
Break
10:30am - 11:30am
Uric Acid as an Independent Marker of Metabolic Syndrome
Speakers:
David Perlmutter, MD, FACN, ABIHM
11:30am - 12:00pm
Panel Discussion
12:00pm - 1:00pm
Lunch
1:00pm - 2:00pm
Insulin: When Things Go Wrong and No One Notices
Speakers:
Elizabeth Broham, MD, RD
2:00pm - 3:00pm
Dysautonomia: An Emerging Post-Pandemic Problem
Speakers:
Shilpa P. Saxena, MD
3:00pm - 3:30pm
Break
3:30pm - 4:30pm
Patterns, Connections and Clinical Pearls: Stress, Sleep and Diet
Speakers:
Shilpa P. Saxena, MD
4:30pm - 5:00pm
Summary of Day One
Speakers:
Jeff Bland, PhD

Day Two April 22, 2023

7:00am - 8:00am
Breakfast
8:00am - 9:00am
The Story of the Glacocalyx
Speakers:
Michael Twyman, MD
9:00am - 10:00am
Nitric Oxide: Beyond Hypertension
Speakers:
Nathan Bryan, PhD
10:00am - 10:30am
Break
10:30am - 12:00pm
Cardiometabolic Physiology as a Health Barometer
Speakers:
Thomas G. Guilliams, PhD
12:00pm - 1:00pm
Lunch
1:00pm - 2:00pm
Getting Results: Where Medicine and Lifestyle Collide
Speakers:
Cheng Ruan, MD
2:00pm - 3:00pm
Patterns, Connections and Clinical Pearls: Hormones, Infections and Genetics
Speakers:
Regina S. Druz, MD, MBA, MS, FACC
3:00pm - 3:30pm
Break
3:30pm - 4:30pm
The Top 5 Nutrients to Level Up Your Cardiometabolic Protocols
Speakers:
Shilpa P. Saxena, MD
4:30pm - 5:00pm
Event Summary and Closing Comments
Speakers:
Jeff Bland, PhD
Jeff Bland, PhD
Jeff Bland, PhD
Functional Medicine Founder and Pioneer
Dr. Jeffrey Bland is a personable and highly respected thought leader who has spent more than four decades focused on the improvement of human health. He is known worldwide as the founder of the Functional Medicine movement, which represents his vision for a care model that is grounded in systems biology and informed by research that he has a unique ability to synthesize. His pioneering work has created the Personalized Lifestyle Medicine Institute (PLMI), as well as the Institute for Functional Medicine (IFM), the global leader in Functional Medicine education. Since 1991, hundreds of thousands of healthcare practitioners have participated in PLMI and IFM programs, and this collective knowledge has positively impacted the lives of patients all over the world.
Austin Perlmutter, MD
Austin Perlmutter, MD
Author and Board-Certified Internal Medicine Physician
Dr Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher and international educator. His mission is to help people improve their health by targeting the biological basis of “stuckness” in our brains and bodies. His writing, presentations, podcasts, and online educational programs explore how environmental factors influence our cognitive and mental state and have reached millions. Dr. Perlmutter currently serves as the managing director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he is running a first-of-its kind study exploring the effects of plant nutrients on human aging through epigenetics.
David Perlmutter, MD, FACN, ABIHM
David Perlmutter, MD, FACN, ABIHM
Author and World-Renowned Neurologist
Dr. Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. Dr. Perlmutter received his M.D. degree from the University of Miami School of Medicine where he was awarded the Leonard G. Rowntree Research Award. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease and has published extensively in peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition. In addition, he is a frequent lecturer at symposia sponsored by institutions such as the World Bank and IMF, Columbia University, Scripps Institute, New York University, and Harvard University and serves as an Associate Professor at the University of Miami Miller School of Medicine. Dr. Perlmutter’s books have been published in 32 languages and include the #1 New York Times bestseller Grain Brain, The Surprising Truth About Wheat, Carbs and Sugar, with over 1 million copies in print. Other New York Times bestsellers include Brain Maker, The Grain Brain Cookbook, The Grain Brain Whole Life Plan, and Brain Wash, co-written with Austin Perlmutter, M.D. He is the editor of The Microbiome and the Brain authored by top experts in the field and published in December2019 by CRC Press. His latest New York Times bestselling book, Drop Acid, focuses on the pivotal role of uric acid in metabolic diseases, and was published in February 2022.
Elizabeth Broham, MD, RD
Elizabeth Broham, MD, RD
Functional Medicine Educator for Cardiometabolic Conditions
Elizabeth Boham, MD, MS, RD is a physician and nutritionist who practices functional medicine and is the medical director of The Ultrawellness Center in Lenox, MA. Dr. Boham completed her undergraduate degree in nutritional biochemistry at Cornell University and her master’s degree in nutrition and registered dietitian at Columbia University Teacher’s College. She then went on to medical school and is board certified in family medicine. Dr. Boham is a certified functional medicine practitioner who is on the faculty of the Institute for Functional Medicine and has developed a functional nutrition course that is being used to educate physicians and other health professionals worldwide. Dr. Boham has contributed to many articles and recently wrote the chapter on Obesity for the 9th edition of the Rankel Textbook of Family Medicine. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness.
Shilpa P. Saxena, MD
Shilpa P. Saxena, MD
Lifestyle Medicine Leader and Group Visit Pioneer
Shilpa P. Saxena, MD, IFMCP is a Board-Certified family physician whose passion and purpose come to life through an uncompromising dedication to the ‘health’ and ‘care’ aspects of healthcare. In July 2019, her practice joined Forum Health, a nationwide provider of personalized health services. Beyond continuing to practice as Medical Director of Forum Health Tampa, Dr. Saxena serves as the corporate-wide Chief Medical Officer at Forum Health. Her commitment to professional growth is evident. In addition to almost 20 years of progressive patient care, Dr. Saxena serves as Faculty with the Institute for Functional Medicine, as well as faculty roles with the Andrew Weil Center for Integrative Medicine, Faculty, George Washington University’s Metabolic Medicine Institute, University of Miami Miller School of Medicine’s Department of Family Medicine and Community Health and Universidad San Ignacio de Loyola (Lima, Perú). As a consummate teacher, she is on a mission to get simple, actionable, lifestyle-based solutions to anyone in the public interested in helping themselves heal. Through her Self Care Collective online workshop series, she continues to marry the science of healing with the art of patient education and empowerment. Dr. Saxena is internationally known for her contributions to the development and institution of the lifestyle-based group medical appointment model with her Group Visit Toolkits and has been awarded for her work with her online patient education platform, Living Wellness University. Dr. Saxena graduated from the University of Florida College of Medicine through the prestigious Junior Honors Medical Program, and completed her Family Practice residency training at St. Vincent’s Medical Center in Jacksonville, Florida while serving as Chief Resident and receiving additional Certification in Low-Risk Obstetrics.
Michael Twyman, MD
Michael Twyman, MD
Functional Medicine Expert in Heart Disease
Dr. Michael Twyman is a board-certified cardiologist who focuses on the prevention and early detection of heart disease. Dr. Twyman completed his cardiovascular training at St Louis University after he completed a 4-year active duty tour as an internist at Naval Hospital Beaufort. He has been in private practice since 2012. Heart Attack Prevention is his passion. He utilizes the best of conventional medicine, integrative/functional medicine, quantum medicine, and biohacking to get to the root cause of the patient’s cardiovascular issues.
Nathan Bryan, PhD
Nathan Bryan, PhD
International Leader in Nitric Oxide Biochemistry
Dr. Bryan is an international expert in nitric biochemistry and molecular medicine. His more than 20 years in academic research led to many seminal discoveries and has resulted in dozens of issued U.S. and International patents. Products from his innovations are the most successful nitric oxide products in the market and are responsible for hundreds of millions of dollars in revenue around the globe. Most recently, Dr. Bryan has his nitric oxide drug technology in phase 3 clinical trials for COVID-19, Ischemic heart disease, and diabetic ulcers.
Thomas G. Guilliams, PhD
Thomas G. Guilliams, PhD
Molecular Immunology Expert
Tom earned his Ph.D. in 1996 from the Medical College of Wisconsin (Milwaukee), where he studied molecular biology/immunology. After his graduate studies, he joined Ortho Molecular Products- a premier physician channel dietary supplement manufacturer- establishing the roles of both science and regulatory affairs. Since that time, he has become an expert in the mechanisms, actions and therapeutic uses of nutritional and non-pharmacological agents, as well as the complex regulatory and quality issues related to dietary supplement manufacturing and marketing. This expertise allowed him to begin writing and teaching, and in 2014 he began writing a series of teaching manuals (Road maps) that outline and evaluate the evidence for the principles and protocols that are fundamental to the functional and integrative medical community. These textbooks explore the root cause pathophysiology of complex chronic diseases, along with the evidence and mechanisms for non-pharmacological therapeutic solutions. Tom teaches at the University of Wisconsin- Madison School of Pharmacy, where he holds an appointment as an Adjunct Associate Professor, and lectures widely to a range of healthcare professionals interested in leveraging lifestyle and natural agents as first-line therapies. Today, Tom serves as a consultant to organizations within the natural products, integrative and functional medicine space where he endeavors to make a real difference in the health and lives of millions. He lives (and works) off the beaten path outside of Stevens Point, Wisconsin with his family; where he has too many hobbies to list here.
Cheng Ruan, MD
Cheng Ruan, MD
Expert Practice Innovation and Wearable Technology Integration
Regina S. Druz, MD, MBA, MS, FACC
Regina S. Druz, MD, MBA, MS, FACC
Integrative Cardiologist and Functional Medicine Expert in Cardiometabolic Conditions
Dr. Druz is an integrative cardiologist and a certified functional medicine physician who created Fit in Your GENES, an integrative cardiology program leveraging data analytics for personalized cardiovascular medicine. After completing her residency and fellowship training at Weill Cornell School of Medicine and New Yor Presbyterian Hospital, Dr. Druz specialized in non-invasive cardiology, with a focus on cardiac imaging. A nationally recorgnized leader in the cardiovascular community, Dr. Druz worked in a variety of settings, such as academia, community and private practice. Discovering her passion for functional medicine, Dr. Druz developed a sustainable model for integrative cardiology, expanding it into hospital and private practice.

Date

Apr 21 - 22 2023
Expired!

Time

7:00 am - 7:00 pm

Location

LIVE

Organizer

OrthoMolecular Products
OrthoMolecular Products
Website
https://www.orthomolecularproducts.com/

Speakers

  • Austin Perlmutter, MD
    Austin Perlmutter, MD
    Author and Board-Certified Internal Medicine Physician

    Dr Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher and international educator. His mission is to help people improve their health by targeting the biological basis of “stuckness” in our brains and bodies. His writing, presentations, podcasts, and online educational programs explore how environmental factors influence our cognitive and mental state and have reached millions. Dr. Perlmutter currently serves as the managing director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he is running a first-of-its kind study exploring the effects of plant nutrients on human aging through epigenetics.

  • Elizabeth Broham, MD, RD
    Elizabeth Broham, MD, RD
    Functional Medicine Educator for Cardiometabolic Conditions

    Elizabeth Boham, MD, MS, RD is a physician and nutritionist who practices functional medicine and is the medical director of The Ultrawellness Center in Lenox, MA. Dr. Boham completed her undergraduate degree in nutritional biochemistry at Cornell University and her master’s degree in nutrition and registered dietitian at Columbia University Teacher’s College. She then went on to medical school and is board certified in family medicine. Dr. Boham is a certified functional medicine practitioner who is on the faculty of the Institute for Functional Medicine and has developed a functional nutrition course that is being used to educate physicians and other health professionals worldwide. Dr. Boham has contributed to many articles and recently wrote the chapter on Obesity for the 9th edition of the Rankel Textbook of Family Medicine. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness.

  • Shilpa P. Saxena, MD
    Shilpa P. Saxena, MD
    Lifestyle Medicine Leader and Group Visit Pioneer

    Shilpa P. Saxena, MD, IFMCP is a Board-Certified family physician whose passion and purpose come to life through an uncompromising dedication to the ‘health’ and ‘care’ aspects of healthcare.

    In July 2019, her practice joined Forum Health, a nationwide provider of personalized health services.

    Beyond continuing to practice as Medical Director of Forum Health Tampa, Dr. Saxena serves as the corporate-wide Chief Medical Officer at Forum Health.

    Her commitment to professional growth is evident. In addition to almost 20 years of progressive patient care, Dr. Saxena serves as Faculty with the Institute for Functional Medicine, as well as faculty roles with the Andrew Weil Center for Integrative Medicine, Faculty, George Washington University’s Metabolic Medicine Institute, University of Miami Miller School of Medicine’s Department of Family Medicine and Community Health and Universidad San Ignacio de Loyola (Lima, Perú).

    As a consummate teacher, she is on a mission to get simple, actionable, lifestyle-based solutions to anyone in the public interested in helping themselves heal. Through her Self Care Collective online workshop series, she continues to marry the science of healing with the art of patient education and empowerment.

    Dr. Saxena is internationally known for her contributions to the development and institution of the lifestyle-based group medical appointment model with her Group Visit Toolkits and has been awarded for her work with her online patient education platform, Living Wellness University.

    Dr. Saxena graduated from the University of Florida College of Medicine through the prestigious Junior Honors Medical Program, and completed her Family Practice residency training at St. Vincent’s Medical Center in Jacksonville, Florida while serving as Chief Resident and receiving additional Certification in Low-Risk Obstetrics.

  • Michael Twyman, MD
    Michael Twyman, MD
    Functional Medicine Expert in Heart Disease

    Dr. Michael Twyman is a board-certified cardiologist who focuses on the prevention and early detection of heart disease. Dr. Twyman completed his cardiovascular training at St Louis University after he completed a 4-year active duty tour as an internist at Naval Hospital Beaufort. He has been in private practice since 2012. Heart Attack Prevention is his passion. He utilizes the best of conventional medicine, integrative/functional medicine, quantum medicine, and biohacking to get to the root cause of the patient’s cardiovascular issues.

  • Nathan Bryan, PhD
    Nathan Bryan, PhD
    International Leader in Nitric Oxide Biochemistry

    Dr. Bryan is an international expert in nitric biochemistry and molecular medicine. His more than 20 years in academic research led to many seminal discoveries and has resulted in dozens of issued U.S. and International patents. Products from his innovations are the most successful nitric oxide products in the market and are responsible for hundreds of millions of dollars in revenue around the globe. Most recently, Dr. Bryan has his nitric oxide drug technology in phase 3 clinical trials for COVID-19, Ischemic heart disease, and diabetic ulcers.

  • Cheng Ruan, MD
    Cheng Ruan, MD
    Expert Practice Innovation and Wearable Technology Integration
  • Regina S. Druz, MD, MBA, MS, FACC
    Regina S. Druz, MD, MBA, MS, FACC
    Integrative Cardiologist and Functional Medicine Expert in Cardiometabolic Conditions

    Dr. Druz is an integrative cardiologist and a certified functional medicine physician who created Fit in Your GENES, an integrative cardiology program leveraging data analytics for personalized cardiovascular medicine. After completing her residency and fellowship training at Weill Cornell School of Medicine and New Yor Presbyterian Hospital, Dr. Druz specialized in non-invasive cardiology, with a focus on cardiac imaging. A nationally recorgnized leader in the cardiovascular community, Dr. Druz worked in a variety of settings, such as academia, community and private practice. Discovering her passion for functional medicine, Dr. Druz developed a sustainable model for integrative cardiology, expanding it into hospital and private practice.

  • Jeff Bland, PhD
    Jeff Bland, PhD
    Functional Medicine Founder and Pioneer

    Dr. Jeffrey Bland is a personable and highly respected thought leader who has spent more than four decades focused on the improvement of human health.

    He is known worldwide as the founder of the Functional Medicine movement, which represents his vision for a care model that is grounded in systems biology and informed by research that he has a unique ability to synthesize. His pioneering work has created the Personalized Lifestyle Medicine Institute (PLMI), as well as the Institute for Functional Medicine (IFM), the global leader in Functional Medicine education. Since 1991, hundreds of thousands of healthcare practitioners have participated in PLMI and IFM programs, and this collective knowledge has positively impacted the lives of patients all over the world.

  • David Perlmutter, MD, FACN, ABIHM
    David Perlmutter, MD, FACN, ABIHM
    Author and World-Renowned Neurologist

    Dr. Perlmutter is a Board-Certified Neurologist and six-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition.

    Dr. Perlmutter received his M.D. degree from the University of Miami School of Medicine where he was awarded the Leonard G. Rowntree Research Award. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease and has published extensively in
    peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition. In addition, he is a frequent lecturer at symposia sponsored by institutions such as the World Bank and IMF, Columbia University, Scripps Institute, New York University, and Harvard University and serves as an Associate Professor at the University of Miami Miller School of Medicine.

    Dr. Perlmutter’s books have been published in 32 languages and include the #1 New York Times bestseller Grain Brain, The Surprising Truth About Wheat, Carbs and Sugar, with over 1 million copies in print. Other New York Times bestsellers include Brain Maker, The Grain Brain Cookbook, The Grain Brain Whole Life Plan, and Brain Wash, co-written with Austin Perlmutter,
    M.D. He is the editor of The Microbiome and the Brain authored by top experts in the field and published in December2019 by CRC Press. His latest New York Times bestselling book, Drop Acid, focuses on the pivotal role of uric acid in metabolic diseases, and was published in February 2022.

  • Thomas G. Guilliams, PhD
    Thomas G. Guilliams, PhD
    Molecular Immunology Expert

    Tom earned his Ph.D. in 1996 from the Medical College of Wisconsin (Milwaukee), where he studied molecular biology/immunology. After his graduate studies, he joined Ortho Molecular Products- a premier physician channel dietary supplement manufacturer- establishing the roles of both science and regulatory affairs. Since that time, he has become an expert in the mechanisms, actions and therapeutic uses of nutritional and non-pharmacological agents, as well as the complex regulatory and quality issues related to dietary supplement manufacturing and marketing. This expertise allowed him to begin writing and teaching, and in 2014 he began writing a series of teaching manuals (Road maps) that outline and evaluate the evidence for the principles and protocols that are fundamental to the functional and integrative medical community. These textbooks explore the root cause pathophysiology of complex chronic diseases, along with the evidence and mechanisms for non-pharmacological therapeutic solutions. Tom teaches at the University of Wisconsin- Madison School of Pharmacy, where he holds an appointment as an Adjunct Associate Professor, and lectures widely to a range of healthcare professionals interested in leveraging lifestyle and natural agents as first-line therapies. Today, Tom serves as a consultant to organizations within the natural products, integrative and functional medicine space where he endeavors to make a real difference in the health and lives of millions. He lives (and works) off the beaten path outside of Stevens Point, Wisconsin with his family; where he has too many hobbies to list here.

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