It is well recognized that individuals who suffer from sleep disturbances have altered composition of their intestinal microbiome. The question has been whether this relationship is coincidental or whether there is a physiological mechanism that connects these observations together in a systematic way that allows for a treatment of the primary cause of both conditions.

Recent research has shown that there is a mechanistic connection between sleep and the gut-immune-brain network. It is now recognized that poor sleep induces changes in the composition of the intestinal microbiome which in turn further alters sleep quality and duration. In turn alterations in the intestinal microbiome and its connection to dysbiosis can trigger sleep disturbances. The discovery of this “push-pull” relationship between sleep and gut-immune-brain function opens the door for new therapeutic approaches to the treatment of sleep disorders.

This conference will focus on the development of understanding of the connection between the neurobiology of sleep and the functional status of the gut-immune-brain network. This conference will provide information related to the assessment of alterations in sleep quality and functional status of the gut-immune-brain network. Personalized clinical approaches to remediation of alterations in the sleep-gut-immune function will be provided from the understanding of the principle factors that drive alterations in this network.

Jeffrey Bland PhD
Peter Bongiorno, ND
Professor John Groeger

Sponsor: Microbiome Labs


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