From Insight to Implementation: Using Immunometabolic Biomarkers to Assess, Personalize, and Scale Patient Care
Course Description
Chronic disease is increasingly driven by underlying immunometabolic dysfunction, yet many clinicians lack practical tools to identify these processes early and translate findings into meaningful clinical action. This webinar explores the science and clinical utility of inflammatory and immunometabolic biomarkers, including emerging applications of the Systemic Immune-Inflammation Index (SII) and Systemic Inflammation Response Index (SIRI), and their role in patient assessment, risk stratification, intervention planning, and ongoing monitoring.
Attendees will examine the relationship between immunometabolic dysfunction and chronic disease, review current evidence supporting biomarker-guided care, and explore real-world clinical applications and early outcomes data. The session will also address practical strategies for integrating these insights into everyday practice, helping clinicians implement personalized, evidence-informed interventions while improving patient engagement, clinical efficiency, and scalability.
By combining scientific foundations with practical implementation, this session will provide attendees with actionable approaches to assessing and improving immunometabolic health in clinical practice.
Learning Objectives
- Review the relationship between immunometabolic dysfunction, chronic inflammation, and chronic disease development.
- Examine the clinical utility of inflammatory and immunometabolic biomarkers, including the Systemic Immune-Inflammation Index (SII) and Systemic Inflammation Response Index (SIRI), in patient assessment and monitoring.
- Explore emerging evidence and real-world clinical applications of biomarker-guided interventions.
- Discuss practical approaches for translating biomarker insights into personalized, evidence-informed care strategies.
- Consider implementation strategies that support patient engagement, clinical efficiency, and scalable delivery of care within modern practice settings.
Agenda & Speakers
- Dr. Jeff Bland: immunometabolic dysfunction, chronic disease, and the science behind inflammatory biomarkers (30 min)
- Dr. Austin Perlmutter: biomarker-guided assessment, research with clinical evidence, and emerging applications of SII/SIRI (30 min)
- Dr. Jeff Gladd: translating biomarker insights into personalized, scalable clinical care (30 min)
- Panel discussion: 30-minute discussion with all speakers
Speakers
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Jeff Bland, PhDJeffrey Bland, PhD, is a pioneering figure in the food-is-medicine movement and a leading expert in nutritional biochemistry. As founder of Big Bold Health, he now focuses on longevity through immune health, championing the concept of immune rejuvenation as a pathway to healthy aging. Dr. Bland’s work highlights the powerful role of plant polyphenols and omega-3 fatty acids in supporting immune resilience. Widely known as the “father of Functional Medicine,” he has spent more than 40 years advancing nutrition science, regenerative agriculture, and personalized approaches to lifelong vitality.
Dr. Bland began his career in academia as a university professor. In the early 1980s, he became a protégé of two-time Nobel Laureate, Dr. Linus Pauling. Dr. Bland then spent decades as a natural products industry insider and entrepreneur, while also serving as a scientific advisor and mentor to dynamic founders and leading brands.
A lifelong educator, Dr. Bland has traveled the world many times over as a renowned speaker. In 1991, he and his wife, Susan, founded The Institute for Functional Medicine. In 2012, they established another educational nonprofit called The Personalized Lifestyle Medicine Institute, which brings together researchers, clinicians, industry leaders, and other stakeholders to focus on new models of healthcare delivery, advancements in medical nutrition therapy, and exciting emerging science.
Dr. Bland is the author of The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life, as well as additional books and many research papers. His next book will be published by HarperCollins in March 2027. The Nourished Gene: Rejuvenate Your Immunity, Reverse Chronic Symptoms, and Activate Your Longevity is now available for pre-order from all major booksellers.
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Austin Perlmutter, MDDr Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher and international educator. His mission is to help people improve their health by targeting the biological basis of “stuckness” in our brains and bodies. His writing, presentations, podcasts, and online educational programs explore how environmental factors influence our cognitive and mental state and have reached millions. Dr. Perlmutter currently serves as the managing director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he is running a first-of-its kind study exploring the effects of plant nutrients on human aging through epigenetics.
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Jeff Gladd, MDAs Chief Medical Officer, Dr. Jeff Gladd, MD advises on company and product direction with the perspective of integrative and family medicine. He has been in this role with Fullscript since 2019. Dr. Gladd graduated from the Indiana University School of Medicine in 2001 and after successfully opening a family practice, shifted focus toward health promoting care by completing the University of Arizona Integrative Medicine fellowship program under the direction of Dr. Andrew Weil, MD in 2009 and opening the Parkview Health Center for Integrative Medicine. In 2010, Dr. Gladd opened GladdMD Integrative Medicine, blending health-promoting care with high access technology. In 2011, he created and launched the web’s first nutrient depletion calculator, Mytavin.com. With the success of GladdMD and Mytavin, Dr. Gladd has become a sought after speaker in his field, speaking at TEDx and being featured in various industry publications.
