Decoding Healthspan: Integrating Genetic Insights for Inflammaging — From Hormones to Gut Health
Course Description
This advanced educational program explores the clinical integration of genetic insights to better understand and address the biological drivers of inflammaging, oxidative stress, hormonal resilience, and gut integrity. Through a precision medicine lens, faculty will translate emerging genomic science into practical, patient-centered strategies that support healthy ageing and metabolic longevity.
Participants will examine clinically relevant genetic variants using dnalife’s DNA Core, DNA Hormones, and DNA Gut assessments, exploring their impact on inflammatory tone, antioxidant defense capacity, endocrine function, and gut–environment interactions. Clinicians will gain clarity on both the clinical utility and limitations of genetic testing, with emphasis on translating genomic data into actionable, individualized care plans. Focus will be placed on interpreting results within the broader context of systems biology, lifestyle medicine, and personalized therapeutic strategy to optimize long-term healthspan outcomes.
Grounded in PLMI’s commitment to evidence-informed, clinically actionable education, this course equips practitioners to move beyond theoretical genomics — integrating precision insights into real-world assessment, strategic intervention, and sustainable patient care.
Program Sessions
Targeted Support for Healthy Ageing Using Genetic Insights
Dr Denise Furness, PhD
Using a clinical case example, key genetic variants that influence inflammaging and antioxidant status will be explored. Practical applications and clinical utility of genetic testing for personalised healthy ageing strategies will be discussed.
Understanding the Genetics of Gut Health and Clinical Application
Dr Devan Szczepanski, MD
Gene–environment interactions play a significant role in shaping an individual’s gut health. This session will explore the genetic factors influencing gut function and discuss their practical application in clinical settings.
Speakers
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Denise Furness, PhDDr Denise Furness, PhD is a molecular geneticist and functional medicine practitioner. She is a pioneer in the field of nutrigenomics and epigenetics (precision medicine) with 20 years’ experience.
Denise began her career as a research scientist focusing on folate nutrigenomics, methylation, and DNA damage. She has published her work in peer reviewed journals and won numerous awards for her research and conference presentations.
In 2012 she founded Your Genes and Nutrition and began applying her knowledge in clinical practice. Denise has a special interest in fertility, thyroid and autoimmunity (after recovering from autoimmune thyroid disease herself), as well as healthy ageing. She is currently running a biological ageing study, aimed at improving mental health and naturally slowing the ageing process. -
Devan Szczepanski, MD, MSDr. Devan Szczepanski is a Board-Certified Family Medicine Physician and a global leader in genomic and nutritional medicine. With a graduate degree in Neuropsychology and advanced certifications in genomic and nutritional medicine, she has spent over a decade pioneering gene-based healthcare, transforming the health of more than 20,000 patients worldwide.
As the founder of Reformative Medicine®, Dr. Szczepanski integrates cutting-edge genomic science with personalized healthcare strategies, bridging the gap between innovative research and practical clinical application. Her approach blends both allopathic and naturopathic philosophies, creating a precision-based, patient-centered model for achieving optimal health.
A respected educator, speaker, and healthcare innovator, Dr. Szczepanski is committed to redefining the future of medicine. Through her work at NuWell Medicine™, she empowers both patients and medical professionals with science-backed, gene-based solutions to enhance longevity, wellness, and disease prevention.
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Michelle Leary, ND, IFMCPDr. Michelle Leary, ND, IFMCP is a recognized leader in functional and personalized lifestyle medicine, serving as Director of Functional Medicine at Vida Integrated Health, where she oversees a regional network of physicians and nutrition professionals. She established and has directed a collaborative residency program with the Institute for Functional Medicine for over five years, cultivating the next generation of physician leaders. A clinical investigator on the LIFE-HOUSE trial, she has also contributed to peer-reviewed research and lectures internationally on systems medicine and precision health. Beyond her clinical and leadership roles, Dr. Leary advises on the strategic adoption of AI technologies in integrative medicine, helping physicians implement innovative tools to enhance decision-making and patient care.
