Beyond Genetics: DNA Methylation, Epigenetic Clocks, and Biomarkers for Real-World Care
- 5x pre-recorded videos with Dr. Loren Clarke; approximately 45 mins each
- Module 1: Genetics 101 — DNA → RNA → Protein (quick refresher)
- Module 2: Epigenetics 101 — gene regulation and methylation basics
- Module 3: TruD Biological Clocks — what they are and what they measure
- Module 4: Building the Clocks — how epigenetic clocks are developed and validated
- Module 5: Epigenetic Biomarkers — what to look at and how to interpret results. And how providers are currently using these biomarkers in practice.
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Event Information
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Speaker
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Loren Clarke, MDI am a board-certified pathologist and physician-executive with 25 years of experience advancing molecular diagnostics from initial concept through clinical adoption. In senior industry leadership roles at Myriad Genetics, DermTech, and now TruDiagnostic, I have led clinical strategy, evidence generation, and medical affairs for multiple biomarker-driven clinical tests, demonstrating their analytical and clinical performance through rigorous study designs, peer-reviewed publications, and clear clinical value narratives for clinicians, payers, patients, and regulators. My academic background at Penn State Hershey Medical Center included leadership roles in molecular pathology and close collaboration with multidisciplinary clinical and laboratory teams, grounding my work in the practical aspects of real-world diagnostic decision-making. I bring a patient-centered, outcomes-driven approach to diagnostics, with extensive experience guiding cross-functional teams across R&D, clinical development, regulatory approval, and commercial execution.
