Michael Fenech, PhD

Professor Michael Fenech is recognised internationally for his research in nutritional genomics and genetic toxicology and for developing the cytokinesis-block micronucleus (CBMN) assay which is a standard method used internationally to measure DNA damage in human cells. The CBMN assay has been endorsed by the International Atomic Energy Agency and the OECD for in vivo radiation biodosimetry and in vitro testing of genotoxins respectively. His key goal is to determine the nutritional and environmental requirements for DNA damage prevention. In 2003 Dr Fenech proposed a novel ageing and disease prevention strategy based on personalised diagnosis and prevention of DNA damage by appropriate diet/life-style intervention, which has led to the Genome Health Clinic concept. In 2003-2009 his laboratory further developed the CBMN assay into a ‘cytome’ assay consisting of six complementary biomarkers of DNA damage and cytotoxicity which is now published in Nature Protocols. He co-founded the HUMN projects on micronuclei in human populations (www.humn.org) and is a member of the coordinating group and co-founder of the Micronutrients Genomics Project which he has been leading since July 2011. His research is currently also focused on (i) the impact of nutrition and psychological stress on telomere integrity and (ii) personalised nutrition for dementia prevention and cancer growth control. In 2014 he was elected Foundation President of the Asia-Pacific Nutrigenomics and Nutrigenetics Organisation (APNNO). Since 2010 he has been an invited speaker at 45 international conferences (9 plenary lectures). His H-index is 78 based on 26,580 total career citations according to Google Scholar.